Dataset | Set_04_DMproB_versus_LMproB.phenotype_DMproB_versus_LMproB.cls #DMproB_versus_LMproB |
Phenotype | phenotype_DMproB_versus_LMproB.cls#DMproB_versus_LMproB |
Upregulated in class | DMproB |
GeneSet | NCI_IL12-MEDIATED SIGNALING EVENTS |
Enrichment Score (ES) | 0.6266885 |
Normalized Enrichment Score (NES) | 1.5785547 |
Nominal p-value | 0.0018018018 |
FDR q-value | 0.19399467 |
FWER p-Value | 0.909 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | EBI3 | 23193 | 4 | 5.900 | 0.1064 | Yes | ||
2 | RELB | 17942 | 179 | 2.396 | 0.1403 | Yes | ||
3 | IL1B | 14431 | 253 | 2.069 | 0.1738 | Yes | ||
4 | STAT3 | 5525 9906 | 266 | 2.009 | 0.2094 | Yes | ||
5 | BCL3 | 8654 | 305 | 1.927 | 0.2422 | Yes | ||
6 | NFKB2 | 23810 | 341 | 1.794 | 0.2727 | Yes | ||
7 | ARRB2 | 20806 | 357 | 1.753 | 0.3036 | Yes | ||
8 | GADD45G | 21637 | 401 | 1.662 | 0.3313 | Yes | ||
9 | CYLD | 18532 | 405 | 1.659 | 0.3611 | Yes | ||
10 | BCL10 | 15397 | 471 | 1.553 | 0.3857 | Yes | ||
11 | IL12A | 4913 | 492 | 1.522 | 0.4121 | Yes | ||
12 | STAT5A | 20664 | 502 | 1.497 | 0.4387 | Yes | ||
13 | MAPK14 | 23313 | 503 | 1.495 | 0.4657 | Yes | ||
14 | STAT4 | 14251 9907 | 557 | 1.405 | 0.4882 | Yes | ||
15 | IL2RG | 24096 | 667 | 1.235 | 0.5047 | Yes | ||
16 | MAP3K14 | 11998 | 807 | 1.093 | 0.5169 | Yes | ||
17 | CD3D | 19473 | 932 | 1.000 | 0.5283 | Yes | ||
18 | RAN | 5356 9691 | 933 | 1.000 | 0.5464 | Yes | ||
19 | IL27RA | 11949 | 1176 | 0.825 | 0.5482 | Yes | ||
20 | CREBBP | 22682 8783 | 1315 | 0.732 | 0.5540 | Yes | ||
21 | TNFAIP3 | 19810 | 1333 | 0.722 | 0.5661 | Yes | ||
22 | BIRC2 | 4397 4398 | 1334 | 0.722 | 0.5792 | Yes | ||
23 | CHUK | 23665 | 1368 | 0.706 | 0.5901 | Yes | ||
24 | TYK2 | 12058 19215 | 1482 | 0.637 | 0.5955 | Yes | ||
25 | IL6ST | 4920 | 1509 | 0.623 | 0.6054 | Yes | ||
26 | IKBKB | 4907 | 1513 | 0.621 | 0.6164 | Yes | ||
27 | NFKB1 | 15160 | 1638 | 0.564 | 0.6199 | Yes | ||
28 | NFKBIA | 21065 | 1694 | 0.538 | 0.6267 | Yes | ||
29 | ATF2 | 4418 2759 | 2029 | 0.404 | 0.6159 | No | ||
30 | NOD2 | 6384 | 2275 | 0.332 | 0.6087 | No | ||
31 | GADD45B | 19935 | 2318 | 0.321 | 0.6122 | No | ||
32 | STAT2 | 19840 | 2338 | 0.316 | 0.6169 | No | ||
33 | MALT1 | 6274 | 2732 | 0.225 | 0.5998 | No | ||
34 | IL12RB1 | 3916 18582 | 2889 | 0.201 | 0.5950 | No | ||
35 | CD86 | 1660 22601 | 3103 | 0.174 | 0.5866 | No | ||
36 | SYK | 21636 | 3556 | 0.125 | 0.5645 | No | ||
37 | PRF1 | 20011 | 3634 | 0.120 | 0.5625 | No | ||
38 | XPO1 | 4172 | 3925 | 0.101 | 0.5486 | No | ||
39 | TNF | 23004 | 4343 | 0.080 | 0.5275 | No | ||
40 | TNFRSF1A | 1181 10206 | 4442 | 0.076 | 0.5236 | No | ||
41 | IL27 | 17636 | 4541 | 0.072 | 0.5196 | No | ||
42 | IL18RAP | 14262 | 4611 | 0.070 | 0.5172 | No | ||
43 | FBXW11 | 20926 | 4860 | 0.062 | 0.5049 | No | ||
44 | B2M | 72 14882 | 4935 | 0.060 | 0.5020 | No | ||
45 | IL12RB2 | 17128 | 5412 | 0.049 | 0.4771 | No | ||
46 | GZMB | 21810 | 5765 | 0.041 | 0.4589 | No | ||
47 | TBX21 | 20276 | 5824 | 0.040 | 0.4565 | No | ||
48 | ERC1 | 1013 17021 995 1136 | 6634 | 0.027 | 0.4133 | No | ||
49 | CCL4 | 1362 20730 | 6983 | 0.022 | 0.3949 | No | ||
50 | PIK3R1 | 3170 | 7282 | 0.019 | 0.3791 | No | ||
51 | ATM | 2976 19115 | 7356 | 0.018 | 0.3755 | No | ||
52 | PIAS2 | 1948 5102 | 7369 | 0.018 | 0.3752 | No | ||
53 | UBE2D3 | 7253 | 8041 | 0.010 | 0.3391 | No | ||
54 | PIK3CA | 9562 | 8241 | 0.008 | 0.3285 | No | ||
55 | CD3E | 8714 | 8370 | 0.006 | 0.3217 | No | ||
56 | MAP2K3 | 20856 | 8518 | 0.004 | 0.3138 | No | ||
57 | IL6 | 16895 | 8787 | 0.002 | 0.2994 | No | ||
58 | IL2 | 15354 | 9362 | -0.004 | 0.2685 | No | ||
59 | IL12B | 20918 | 9683 | -0.007 | 0.2513 | No | ||
60 | RIPK2 | 2528 15935 | 10837 | -0.019 | 0.1894 | No | ||
61 | CD3G | 19139 | 10934 | -0.020 | 0.1845 | No | ||
62 | GZMA | 21343 | 10976 | -0.021 | 0.1827 | No | ||
63 | IL2RA | 4918 | 11136 | -0.023 | 0.1745 | No | ||
64 | IL4 | 9174 | 11378 | -0.026 | 0.1620 | No | ||
65 | JAK2 | 23893 9197 3706 | 11684 | -0.030 | 0.1460 | No | ||
66 | IKBKG | 2570 2562 4908 | 12271 | -0.038 | 0.1151 | No | ||
67 | STAT6 | 19854 9909 | 12623 | -0.044 | 0.0969 | No | ||
68 | SRC | 5507 | 12732 | -0.046 | 0.0919 | No | ||
69 | CCR5 | 8754 4534 | 13005 | -0.051 | 0.0781 | No | ||
70 | IL18R1 | 14263 | 13154 | -0.054 | 0.0711 | No | ||
71 | IL1R1 | 14264 3987 | 13324 | -0.059 | 0.0630 | No | ||
72 | FRAP1 | 2468 15991 | 13684 | -0.070 | 0.0449 | No | ||
73 | LCK | 15746 | 13709 | -0.070 | 0.0449 | No | ||
74 | SPHK2 | 1217 1806 12155 | 13874 | -0.077 | 0.0374 | No | ||
75 | CD247 | 4498 8715 | 13917 | -0.078 | 0.0365 | No | ||
76 | IFNG | 19869 | 14286 | -0.093 | 0.0183 | No | ||
77 | CD4 | 16999 | 14357 | -0.096 | 0.0163 | No | ||
78 | IL18 | 9172 | 14486 | -0.103 | 0.0112 | No | ||
79 | CCL3 | 20317 | 14822 | -0.122 | -0.0046 | No | ||
80 | CD28 | 14239 4092 | 15026 | -0.138 | -0.0131 | No | ||
81 | FASLG | 13789 | 15127 | -0.147 | -0.0159 | No | ||
82 | CD8B | 4502 17418 | 15259 | -0.159 | -0.0201 | No | ||
83 | IL17A | 14289 | 15316 | -0.165 | -0.0201 | No | ||
84 | IL13 | 20461 | 15361 | -0.170 | -0.0194 | No | ||
85 | REL | 9716 | 15371 | -0.171 | -0.0168 | No | ||
86 | GATA3 | 9004 | 15431 | -0.179 | -0.0168 | No | ||
87 | JAK1 | 15827 | 15986 | -0.269 | -0.0418 | No | ||
88 | ETV5 | 22630 | 16024 | -0.278 | -0.0388 | No | ||
89 | RELA | 23783 | 16057 | -0.286 | -0.0354 | No | ||
90 | SOCS1 | 4522 | 16191 | -0.317 | -0.0368 | No | ||
91 | EOMES | 4669 | 16242 | -0.329 | -0.0336 | No | ||
92 | TGFB1 | 18332 | 16317 | -0.350 | -0.0312 | No | ||
93 | TRAF6 | 5797 14940 | 16432 | -0.382 | -0.0305 | No | ||
94 | MAP2K6 | 20614 1414 | 16564 | -0.417 | -0.0300 | No | ||
95 | IL2RB | 22219 | 16614 | -0.432 | -0.0249 | No | ||
96 | PRKCA | 20174 | 16682 | -0.460 | -0.0202 | No | ||
97 | IRF1 | 1336 1258 1433 9182 | 16691 | -0.463 | -0.0122 | No | ||
98 | STAT1 | 3936 5524 | 16743 | -0.486 | -0.0062 | No | ||
99 | CD80 | 22758 | 16793 | -0.510 | 0.0004 | No | ||
100 | RAB7A | 9684 5347 9683 | 16934 | -0.563 | 0.0030 | No | ||
101 | MAPK8 | 6459 | 17529 | -0.879 | -0.0132 | No | ||
102 | MAPK9 | 1233 20903 1383 | 17787 | -1.041 | -0.0083 | No | ||
103 | FOS | 21202 | 17967 | -1.183 | 0.0034 | No | ||
104 | JUN | 15832 | 18330 | -1.748 | 0.0154 | No |